Small vessel cerebral arterioapathy causes include: infection, inflammatory, disease, brain cancers, paraneoplastic syndrome cancers, monogenic conditions, exposure to radiation, or vasoconstrictive drugs.
The diagnosis relies on the patient’s age, family, history, tempo or progression of disease, the presence of systemic signs and extracerebral neurologic deficits, imaging features of the brain and vasculature, and the results of diagnostic tests, including test for inflammatory and cancer, biomarkers, genetic test, CSF, analysis, biopsy of the skin, temporal artery, and brain.