Defined as GFR less than 15 mL/min per 1.73 m2 or a need to start kidney replacement therapy.
Kidney failure affects more than 800,000 people in the US.
The mortality from kidney failure is estimated to be approximately 18% per year, and is a higher mortality rate than observed among patients with heart failure, diabetes, or many cancers.
Kidney failure, disproportionately affects racial and ethnic minority individuals and people with low income.
KF is highly morbid and requires treatment, usually in the form of transplant or three weekly dialysis sessions, for survival.
Most patients in the US with kidney failure are covered by the end stage renal disease (ESRD) program.
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