Kalydeco (Ivacaftor)

Kaylydeco (ivacaftor) available for the treatment of cystic fibrosis, tripling the number of rare gene mutations that the drug is indicated to treat from 10 to 33.

Kalydeco is taken twice a day in either tablet or oral granule form with fat-containing food, and can be prescribed to patients 2 years and older with 1 of the mutations of cystic fibrosis that is responsive to treatment.

If a patient’s genotype is unknown, a mutation test can be used to determine the mutation of

Adverse effects include headache, upper respiratory tract infection, including the common cold, sore throat, nasal or sinus congestion, abdominal pain, diarrhea, rash, nausea, and dizziness.

Kayldeco is also associated with increasing the risk for elevated transaminases and pediatric cataracts.

Not recommended to be taken with a strong CYP3A inducer as it has been shown to diminish the effectiveness of Kayldeco.

Leave a Reply

Your email address will not be published. Required fields are marked *