Juvenile idiopathic arthritis

Refers to all forms of arthritis that begin before the age of 16 years, and persists for more than 6 weeks and are of unknown cause.

Most common chronic rheumatic disease in children.

Prevalence in developed countries between 16 and 150 per 100,000.

Subtype-systemic arthritis-affects males and females equally, accompanied by quotidian fever of at least 2 weeks duration, and may have a non-fixed erythematous rash hepatosplenomegaly, generalized lymphadenopathy or serositis.

Subtype-systemic arthritis-during fever peaks may be associated with abdominal pain or myalgias.

Subtype-systemic arthritis-arthritis is often symmetrical, polyarticular and may develop later in the course of the illness.

Subtype-systemic arthritis-lab abnormalities include anemia, leucocytosis, elevation in the ESR and CRP concentration and thrombocytosis.

Subtype-systemic arthritis-anemia associated with IL-6 induced iron sequestration in the reticuloendothelial system.

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