Herpesvirus 8

Known as Kaposi’s sarcoma-associated herpesvirus and is etiologically linked to Kaposi’s sarcoma, primary effusion lymphoma and a form of multicentric Castleman’s disease.

Virtualy all primary effusion lymphoma cells, Kaposi sarcoma spindle cells carry the Kaposi sarcoma herpesvirus.

Infection signs and symptoms include: fever, arthritis, lymphadenopathy, enlarged spleen, diarrhea and fatigue.

A gammavirus that contains genes with angiogenic activity.

Kaposi sarcoma herpesvirus (KSHV) induced lymphoma is very aggressive with a poor prognosis.

Kaposi sarcoma herpesvirus (KSHV) induced lymphoma manifests pleural effusion in Kaposi sarcoma patients with advanced AIDS, but can rarely be found in HIV negative patients.

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