Known as Kaposi’s sarcoma-associated herpesvirus and is etiologically linked to Kaposi’s sarcoma, primary effusion lymphoma and a form of multicentric Castleman’s disease.
Virtualy all primary effusion lymphoma cells, Kaposi sarcoma spindle cells carry the Kaposi sarcoma herpesvirus.
Infection signs and symptoms include: fever, arthritis, lymphadenopathy, enlarged spleen, diarrhea and fatigue.
A gammavirus that contains genes with angiogenic activity.
Kaposi sarcoma herpesvirus (KSHV) induced lymphoma is very aggressive with a poor prognosis.
Kaposi sarcoma herpesvirus (KSHV) induced lymphoma manifests pleural effusion in Kaposi sarcoma patients with advanced AIDS, but can rarely be found in HIV negative patients.