Gastric polyps

The stomach wall can benign polyppoid growths.

In 40% of patients with benign gastric polyps, the lesions are mucosal in origin and in 60% they are are nonmucosal.

Gastric luminal lesions projecting above the mucosal surface.

Are relatively frequent finding on gastric endoscopy.

Occurs equally in men and women equally.

Multiple in more than 25 percent of paients.

Two-thirds occurring in patients over 60 years.

Hyperplastic polyps and adenomas are relatively more frequent than fundic gland polyps in regions where Helicobacter pylori infection is common.

Some lesions are associated with familial cancer syndromes : familial adenomatous polyposis and hamartomatous polyps are seen in patients with Peutz-Jeghers syndrome.

Subtypes of gastric polyps are divided into nonneoplastic and neoplastic and are also further classified by their association with polyposis syndromes.

Benign polyps of the stomach have an incidence of 0.4% in autopsy series and 3-5% in upper endoscopic series.

Such lesions account for 3.1% of all gastric tumors, and their frequency increases to almost 90% of benign gastric tumors.

Usually asymptomatic, but rarely associated with epigastric pain, gastric outlet obstruction, or bleeding.

Adenomatous polyps have the potential for the development of malignancy.

Gastrointestinal stromal tumors may occur.

Associated bleeding is unusual, but such benign tumors may become inflamed or ulcerate.

Most tumors are found incidentally on endoscopy.

Physical findings are not specific, but in the Peutz-Jeghers syndrome patients may have abnormal pigmentation of the oral mucosa, lips, and digits.

Associated abdominal mass may rarely be present.

Cystic fundic gland polyps are the most common for of gastric polyps accounting for almost 50% of all gastric polyps.

Cystic fundic gland polyps usually found in the fundus and body of the stomach.

Cystic fundic gland polyps associated with sporadic appearance, long-standing proton pump inhibitor (PPI) use, and with familial cancer syndromes.

Cystic fundic gland polyps are benignexcept as associated with rare malignant familial syndromes.

Cystic fundic gland polyps usually multiple when sporadic, and are 1-5 mm with smooth, translucent sessile appearance.

Cystic fundic gland polyps should be sampled but are not required to be removed unless associated with a familial cancer syndrome.

Cystic fundic gland polyps not associated with H pylori, but may be weakly related to PPI use.

Endoscopy used for diagnostic and therapeutic purposes.

Snare biopsies that retrieve the whole specimen are pref2242ed.

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