Benign breast tumor comprised of both epithelial and stromal elements.
Often a palpable breast mass that occurs at peak incidence in the second and third decades of life but can be found in women of all ages.
Approximately 10-15% of lesions are multiple.
Rarely appears in older women.
Prevalence in women older than 40 years is 8-10%.
Most common benign breast tumor in women and the second most common solid tumor of the breast after breast cancer.
Most commonly diagnosed breast tumor in women younger than 30 years.
Diagnosis usually can be made on core needle biopsy.
May develop in 50% of women treated with cyclosporin A after renal transplantation.
Lesions containing in-situ or invasive carcinomas are rare.
Associated with an increased risk of breast cancer.
The presence of atypia is rare with a prevalence of 0.81% and therefore not associated with an increased risk of breast cancer.
Management can be observation or enucleation.
Can be confused clinically and histologically with phylloides tumors.