Erythema toxicum neonatorum


Also known as erythema toxicum, urticaria neonatorum and toxic erythema of the newborn.

A common rash in neonates.

It appears in up to half of newborns carried to term, usually between day 2–5 after birth.

Does not occur outside the neonatal period.

Characterized by blotchy red spots on the skin.

Red spots on skin with overlying white or yellow papules or pustules.

The rash is composed of small papular lesions, each on a separate reddened base.

These lesions may be few or numerous.

Rash typically resolves within first two weeks of life.

Frequently individual lesions will appear and disappear within minutes or hours.

Benign condition.

Cause thought to be an activation of the immune system, But hypersensitivity to detergents in bedsheets and clothing is sometimes suspected.

Causes no discomfort to the infant.

Rash generally disappears spontaneously in about 2 weeks.

The fluid from erythema toxicum lesions will show many eosinophils.

High level of circulating eosinophils, may be seen.

Differential diagnosis may include Herpes simplex virus, Impetigo, neonatal sepsis, Listeria and Varicella

No treatment is indicated.

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