Choroid metastases

Approximately 80% occur in women.

Most common lesions are from breast cancer and lung cancer.

The choroid is the most common site of ocular metastatic disease, because of its rich vascular supply.

An autopsy study of 716 eyes in patients with known systemic malignancy reveal choroidal metastases in 4% of patients.

Choroidal metastases, commonly appear as a yellow lesion and can cause subretinal fluid.

Evaluation includes fundus photography, ultrasonography, and optical coherence tomography.

MRI of the brain and orbits also recommended to assess concomitant involvement of the CNS.

Must be differentiated from other intraocular tumors, particularly choroidal melanoma.

The primary treatment of uveal metastases includes external beam or plaque radiotherapy, systemic chemotherapy, or photodynamic therapy.

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