Biomarkers are biological or physiological measurements that mirror a disease process.
Biomarkers can fall into several different categories: biomarkers of risk, diagnostic biomarkers, and prognostic and predictive biomarkers for treatment.
Biomarkers may or may not represent appropriate targets for treatment.
Defined as a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention.
Ideally, should be accurate, and measurable with simple, inexpensive and repeatable way and carried out in an easily available body fluid such as serum, urine, or prostate fluid.
Risk biomarkers entail germline genetic factors that predetermine risk for developing cancer.