A fluoroquinolone antibiotic that can be administered in tablet form or intravenously.

Traded as delafloxacin.

It works against both gram-positive and gram-negative pathogens, including methicillin-resistance Staphylococcus aureus.

Associated with no drug-drug interactions, aside from co-administration with chelating agents, such as antacids.

Common adverse reactions include: nausea diarrhea, headache, transaminase elevations, and vomiting.

Fluoroquinolones have been associated with tendonitis and tendon rupture, peripheral neuropathy, central nervous system effects, and exacerbations of myasthenia.

Patients with a history of myasthenia graves should not be prescribed this drug

For acute bacterial skin and skin structure infections.

For injection 300 mg by intravenous infusion over 60 minutes, every 12 hours, or a 450-mg tablet orally every 12 hours for 5 to 14 days total duration.

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