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Bedaquiline

And anti-mycobacterial drug that inhibits mycobacterial ATP synthetase and depletes cellular energy stores.

Differs from other anti-mycobacterial drugs and therefore it has the capacity to retain activity against some M tuberculosis isolates resistant to other drugs.

Bedaquiline-pretomanid-linezolid  regimen has a 90% efficacy against highly drug-resistant tuberculosis.

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