“7OH” most commonly refers to 7-hydroxymitragynine.
7OH is an active alkaloid found in kratom (Mitragyna speciosa).
It is a naturally occurring compound in kratom leaves and is one of the primary psychoactive alkaloids in kratom, along with mitragynine.
Kratom is a plant whose leaves are sold in various forms of medicinal and recreational purposes.
It acts as a partial agonist at mu-opioid receptors.
It has higher binding affinity and potency than mitragynine, and contributes significantly to kratom’s opioid-like effects.
It has analgesic, properties, a produce euphoria and sedation at higher doses.
It cause respiratory depression, though typically less severe than traditional opioids
The FDA has not approved kratom or its alkaloids for medical use.
Acts as a partial agonist at mu-opioid receptors.
Has higher binding affinity and potency than mitragynine, which Contributes significantly to kratom’s opioid-like effects.
Individuals may use Kratom to manage chronic pain, depression, anxiety, or opioid withdrawal.
Adverse effects in severe cases may include cardiac arrhythmia is, seizures, respiratory depression, and death.