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Zonisamide

An antiepileptic drug.

Zonegran (zonisamide) Capsules

Adjunctive therapy for treatment of partial seizures in adults with epilepsy.

Zonegran is indicated for use as an adjunctive therapy for treatment of partial seizures in adults with epilepsy.

Approximately 27% of patients treated with experience 75% or more reduction in seizure frequency, while only 12% of placebo-treated patients experienced such reduction.

Common side effects include: ataxia, anorexia, drowsiness, gastrointestinal symptoms,

Rare, but serious side effects include: rash, epidermal necrolysis, aplastic anemia, and agranulocytosis

Mechanisms of action unknown.

Has demonstrated weight-loss efficacy in obese patients.

A daily dose of 400 mg moderately enhances weight loss with diet and lifestyle counseling.

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