Whipple’s triad


Whipple’s triad is a collection of three signs that suggests that a symptoms result from hypoglycaemia that may indicate insulinoma: symptoms of hypoglycaemia, low blood plasma glucose concentration, and relief of symptoms when plasma glucose concentration is increased.

Other name-Whipple’s criteria

Whipple’s triad is stated in various versions. The essential conditions are:

Whipple’s criteria are no longer used to justify surgical exploration for an insulinoma.

The radiological investigation of choice now is endoscopic and/or intraoperative ultrasonography.

Whipple’s triad is not exclusive for insulinoma, and other conditions will also be considered.

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