Terbutaline It is a β2 adrenergic receptor agonist, used as a reliever inhaler in the management of asthma symptoms.



It is also a tocolytic delaying preterm labor for up to 48 hours. 



Brand name Bricanyl .



Pregnancy category C



Routes of administration


Oral-tablets, oral solution, inhalation,  nebulizer solution, SQ



Protein binding 25%



Metabolism: liver



Elimination half-life 11-16 hours



Excretion urine 90% (60% unchanged)



It  is used as a fast-acting bronchodilator, as a short-term asthma treatment and as a tocolytic to delay premature labor. 



The inhaled form of terbutaline starts working within 15 minutes and can last up to 6 hours.



Terbutaline as a treatment for premature labor is an off-label use, and is routinely prescribed to stop contractions.



Side effects: 



Adult — tachycardia, anxiety, nervousness, tremors, headache, hyperglycemia, hypokalemia, hypotension and, rarely, pulmonary edema.



Fetal — tachycardia and hypoglycemia



The tertiary butyl group in terbutaline makes it more selective for β2 receptors. 



Brand names include Bronclyn, Brethine, Bricanyl, Brethaire, and Terbulin.



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