Develop in nearly 10 percent of patients with malignancies.
A rare manifestation of internal cancer.
Caners most likely to develop skin nodules are breast cancer, lung cancer, skin cancer, lymphoma, blood and bone marrow malignancy, kidney and GI malignancies.
Most skin metastases present as solitary nodules, but melanoma and carcinoma of unknown origin may presented with multiple nodules.
Testicle cancer identified with skin metastasis identified in only 0.5% of cases.