SAHA syndrome


Refers to the presence of seborrhoea, acne, hirsutism and alopecia in women.

Can be associated with polycystic ovary syndrome, cystic mastitis, obesity and infertility.

The association of these androgen-dependent cutaneous signs, are classified according to their etiology into four types: (1) idiopathic, (2) ovarian, (3) adrenal, and (4) hyperprolactinemic SAHA.

Generally occurs in young to middle-aged women and involves either the presence of elevated blood levels of androgens or increased androgen-driven peripheral response with normal circulating androgen levels.

Evaluation identifies the cause for peripheral hyperandrogenism and excludes androgen-producing tumors.

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