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SAHA syndrome

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Refers to the presence of seborrhoea, acne, hirsutism and alopecia in women.

Can be associated with polycystic ovary syndrome, cystic mastitis, obesity and infertility.

The association of these androgen-dependent cutaneous signs, are classified according to their etiology into four types: (1) idiopathic, (2) ovarian, (3) adrenal, and (4) hyperprolactinemic SAHA.

Generally occurs in young to middle-aged women and involves either the presence of elevated blood levels of androgens or increased androgen-driven peripheral response with normal circulating androgen levels.

Evaluation identifies the cause for peripheral hyperandrogenism and excludes androgen-producing tumors.

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