Rusfertide (Mimrylo) rusfertide) as a first-in-class hepcidin mimetic to treat erythrocytosis in adults with polycythemia vera (PV).
It helps control red blood cell overproduction and maintain safe hematocrit levels, reducing the need for regular blood removal by phlebotomy.
Acts like hepcidin, a natural hormone that manages iron balance in the body.
Limits iron availability to slow down the creation of new red blood cells.
Given as a weekly injection under the skin.
Keeps hematocrit levels safely under 45%.
Lowers the frequency of therapeutic phlebotomies.
Relieves common chronic symptoms like severe fatigue.
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