Romosozumab is used to treat osteoporosis.



It increases bone formation and decreases bone resorption in postmenopausal women with low bone density. 



It is a humanized monoclonal antibody that targets sclerostin.



Brand name Evenity.



It decreases the risk of fractures of the spine.



Romosozumab is a humanized monoclonal antibody.



Pregnancy category US: N (Not classified yet)



Side effect include: headache, joint pain, and pain at the site of injection, increased the risk of heart attacks, strokes, and deaths from cardiovascular disease.



Two trials found a reduction  rate of vertebral fracture:  73% and 50% lower risk of vertebral fracture after one year of treatment.


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