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Romosozumab

Romosozumab is used to treat osteoporosis.

 

 

It increases bone formation and decreases bone resorption in postmenopausal women with low bone density. 

 

 

It is a humanized monoclonal antibody that targets sclerostin.

 

 

Brand name Evenity.

 

 

It decreases the risk of fractures of the spine.

 

 

Romosozumab is a humanized monoclonal antibody.

 

 

Pregnancy category US: N (Not classified yet)

 

 

Side effect include: headache, joint pain, and pain at the site of injection, increased the risk of heart attacks, strokes, and deaths from cardiovascular disease.

 

 

Two trials found a reduction  rate of vertebral fracture:  73% and 50% lower risk of vertebral fracture after one year of treatment.

 

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