Romosozumab is used to treat osteoporosis.
It increases bone formation and decreases bone resorption in postmenopausal women with low bone density.
It is a humanized monoclonal antibody that targets sclerostin.
Brand name Evenity.
It decreases the risk of fractures of the spine.
Romosozumab is a humanized monoclonal antibody.
Pregnancy category US: N (Not classified yet)
Side effect include: headache, joint pain, and pain at the site of injection, increased the risk of heart attacks, strokes, and deaths from cardiovascular disease.
Two trials found a reduction rate of vertebral fracture: 73% and 50% lower risk of vertebral fracture after one year of treatment.