Have a frequency of 1 in 2000.
More than 10,000 rare diseases.
A rare disease affects more than 200,000 people living in the US.
Affects about 6% of the population in Western societies.
Rare cancers are associated with incidence of less than five or six per hundred thousand person-years. making almost all pediatric cancers rare.
Approximately 30 million people are affected by a rare disease.
More than half of the 30 million people affected by a rare disease or children.
More than 80% of rare diseases have a genetic component.
Most rare diseases are serious and can involve chronic illness, disability and death.
1/3 of children with a rare disease die before their fifth birthday.
Next generation sequencing has improved rates of diagnosis.
Treatments exist for fewer than 5% of individuals with rare conditions.
One in 10 Americans is affected by a rare disease.