A biological product containing fibrinogen and thrombin, 2 proteins in plasma.

It is a dried fibrin sealant to control bleeding during surgery.

Sealant dissolves in blood, triggering a reaction between fibrinogen and thrombin, forming blood clots to stop small blood vessel bleeding when sutures, ligatures, or cautery are ineffective or impractical.

Can be stored at room temperature.

When used with an absorbable gelatin sponge stops bleeding more quickly than the sponge used alone in patients with vascular, spinal, hepatic, and soft tissue surgery.


Most common adverse effects are surgical pain, nausea, constipation, fever, and hypotension.

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