See sirolimus

Originally discovered as an antifungal compound, it later gained attention for its immunosuppressive and anti-cancer properties.

Rapamycin is commonly used in organ transplantation to prevent rejection of the transplanted organ. 

It works by inhibiting the body’s immune response.

Rapamycin has shown promise as an anti-cancer drug and is used to prevent the growth of certain types of tumors. 

It works by inhibiting a protein called mTOR, which plays a crucial role in cell growth and division.

Side effects: may include mouth sores, nausea, diarrhea, high blood pressure, increased blood cholesterol, and impaired wound healing.

Has potential in treating other conditions like tuberous sclerosis complex, hemolytic-uremic syndrome, and certain rare lung diseases.

Immunosuppressant to prevent rejection in organ transplantation.

Macrolide antibiotic derived from a fungus.

Inhibits mTOR kinase which is involved in the regulation of cell growth, survival and response to nutrients.

m-TOR functions as an intermediary in a variety of cell signaling events to regulate cell growth, proliferation, angiogenesis and cell survival.

Suppresses the immune system by blocking T-cell activation and proliferation.

Binds to and inhibits the homologous kinase in mammalian cells , mTOR.

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