Polyglutamine diseases

Hereditary, age dependent, on neurodegenerative disorders resulting from the expansion of exonic CAG repeats in specific but unrelated genes that lead to selective neuronal death).

Nine diseases identified: Huntington’s disease, spinobulbar muscular atrophy, dentatorubral-pallidoluysian atrophy, and spinocerebeller ataxias 1,2,3,6,7,and 17.

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