Pneumococcal infection

Risk factors include frequent episodes of otitis media and day care center attendance in children younger than 2 years.

Young children, elderly persons and black persons of all ages are disproportionately affected by invasive Pneumococcal disease.

Invasive disease 50-100 times more common in HIV infected patients.

Risk factors in HIV patients include lowered CD4+ cell count, history of AIDS associated opportunistic infection or previous pneumococcal infection.

Alcoholism, recent hospitalization and black race associated with increased risk in HIV+ patients.

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