Pilocarpine (Salagen)

A non-selective muscarinic receptor agonist in the parasympathetic nervous system.

Acts at the muscarinic acetylcholine receptor M3.

Stimulates major and minor salivary glands increasing whole saliva production and parotid saliva enhancement.

Used to treat chronic open angle glaucoma and acute angle closure glaucoma.

Acts on a subtype of muscarinic receptor M3 on the iris sphincter muscle promoting contraction and miosis.

Causes the ciliary muscle to contract and opens the trabecular meshwork facilitating the rate aqueous humor exits the eye to decrease intraocular pressure.

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