Describes how the body alters a drug.

Pharmacokinetic factors are such that influence the concentration of drug that will ultimately reach the therapeutic target.

Intake of equal doses of aspirin, β-blockers, or statins yields higher plasma levels in women, partly due to smaller distribution volume and lower clearance compared with men.

With regard to pharmacodynamics, aspirin more potently inhibits platelet aggregation and β-blockers more efficiently reduce exercise-induced angina in men.


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