Describes how the body alters a drug.
Pharmacokinetic factors are such that influence the concentration of drug that will ultimately reach the therapeutic target.
Intake of equal doses of aspirin, β-blockers, or statins yields higher plasma levels in women, partly due to smaller distribution volume and lower clearance compared with men.
With regard to pharmacodynamics, aspirin more potently inhibits platelet aggregation and β-blockers more efficiently reduce exercise-induced angina in men.