Parkinson’s disease dementia

Cognitive symptoms frequent at presentation, with 40-70% developing dementia during the disease course.

Dementia develops at least two years after diagnosis.

Risk factors for the development of dementia include advanced age, more severe motor symptoms and treatment associated visual hallucinations.

Similar to Alzheimer’s but with more visual-spatial deficits, hallucinations, but less severe memory problems.

Share similar neuropathology, cognitive profile and clinical course as those with diffuse Lewy-body disease.

Presence of Lewy bodies in neocortical and paralimbic areas.

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