Multi-cancer early detection (MCED) tests are blood tests designed to screen for signals of many cancer types at once, rather than testing for one cancer at a time.
Most look for cell-free DNA fragments shed by tumors into the bloodstream, checking methylation patterns that can indicate cancer is present.
They do not diagnose cancer — a positive result means further imaging or biopsy is needed to confirm and locate it.
Galleri made by GRAIL, is the best-known MCED test.
It’s been sold since 2021 but isn’t yet FDA-approved.
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