A synthetic progesterone. 

Approved for the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with acquired immunodeficiency syndrome diagnosis.

Seem to stimulate appetite and increase in body weight, although not muscle mass.

Progestins are considered for patients with refractory cachexia and with anorexia as a major distressing symptom.

Body competition of weight gain indicates increased body fat stores instead of lean body tissue.

Associated with an increased risk of thromboembolism with doses of greater than 800 mg per day.

Studies suggest low-quality evidence that it increases weight and appetite with no effect on quality of life or mortality when compared with placebo.

Increase in body weight is dose responsive.

May be associated with edema and impotency.

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