A prion disease.

An epidemic prion disease of humans seem primarily in Papua New Guinea.

Affects the Fore linguistic group of Papua New Guinea.

Predominantly affects adult women and children of both sexes.

It was the practice of the Fore society to consume deceased relatives, resulting in human-to-human prion transmission.

A fatal, transmissible neurodegenerative disease.

Associated with prolonged incubation periods that may exceed five decades, and the disease predominantly affected women and children.

The disease process has disappeared from the Fore population, with the cessation of cannibalism in the late 1950s.


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