Koebner’s disease

The induction by and at the site of trauma to the skin, of disease manifestations typical of the disease elsewhere.

Is a specific disease response to a nonspecific trauma to the skin resulting in the pathogenesis of the disease.

Known as Koebner phenomenon

Refers to skin lesions appearing on lines of trauma.

May result from either a linear exposure or irritation.

Linear lesions after a linear exposure to a causative agent include: molluscum contagiosum, warts and toxicodendron dermatitis.

Warts and molluscum contagiosum lesions can be spread in linear patterns by scratching.

Toxicodendron dermatitis lesions are often linear from brushing up against the poison ivy plant.

Causes that are secondary to scratching rather than an infective or chemical cause include vitiligo, psoriasis, lichen planus, lichen nitidus, pityriasis rubra pilaris, and keratosis follicularis (Darier disease).

The Koebner phenomenon describes skin lesions which appear at the site of injury and may be seen in:


Pityriasis rubra pilaris

Lichen planus

Lichen nitidus


Lichen sclerosus

Elastosis perforans serpiginosa

Kaposi sarcoma

Necrobiosis lipoidica

Systemic Lupus Erythematosus

Juvenile Idiopathic Arthritis

Still disease

A similar response, pathergy, occurs in pyoderma gangrenosum and Behcet’s syndrome..

Reported associated with acute myeloid leukemia.

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