The induction by and at the site of trauma to the skin, of disease manifestations typical of the disease elsewhere.
Is a specific disease response to a nonspecific trauma to the skin resulting in the pathogenesis of the disease.
Known as Koebner phenomenon
Refers to skin lesions appearing on lines of trauma.
May result from either a linear exposure or irritation.
Linear lesions after a linear exposure to a causative agent include: molluscum contagiosum, warts and toxicodendron dermatitis.
Warts and molluscum contagiosum lesions can be spread in linear patterns by scratching.
Toxicodendron dermatitis lesions are often linear from brushing up against the poison ivy plant.
Causes that are secondary to scratching rather than an infective or chemical cause include vitiligo, psoriasis, lichen planus, lichen nitidus, pityriasis rubra pilaris, and keratosis follicularis (Darier disease).
The Koebner phenomenon describes skin lesions which appear at the site of injury and may be seen in:
Psoriasis
Pityriasis rubra pilaris
Lichen planus
Lichen nitidus
Vitiligo
Lichen sclerosus
Elastosis perforans serpiginosa
Kaposi sarcoma
Necrobiosis lipoidica
Systemic Lupus Erythematosus
Juvenile Idiopathic Arthritis
Still disease
A similar response, pathergy, occurs in pyoderma gangrenosum and Behcet’s syndrome..
Reported associated with acute myeloid leukemia.