Iron dextran

Causes anaphylactic-type reactions in approximately 0.7% of hemodialysis patients.

Meta-analysis suggests iron dextran related incidence of anaphylaxis 0.61%.

Death a rare occurrence from anaphylactic reaction.

Two forms: high molecular weight (Dexf2242um) and low molecular weight (In-Fed).

High molecular weight iron dextran is associated with significant toxicities.

Low molecular weight treatment is much safer.

ImFeron a high molecular weight agent is no longer available.

For Infed a retrospective analysis of 61,950 hemodialysis patients with incidents of reactions requiring resuscitative medications was .0016% (Walters).

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