Causes anaphylactic-type reactions in approximately 0.7% of hemodialysis patients.
Meta-analysis suggests iron dextran related incidence of anaphylaxis 0.61%.
Death a rare occurrence from anaphylactic reaction.
Two forms: high molecular weight (Dexf2242um) and low molecular weight (In-Fed).
High molecular weight iron dextran is associated with significant toxicities.
Low molecular weight treatment is much safer.
ImFeron a high molecular weight agent is no longer available.
For Infed a retrospective analysis of 61,950 hemodialysis patients with incidents of reactions requiring resuscitative medications was .0016% (Walters).