Intranasal drug delivery

Nasal tissues are highly vascularized and have good permeability, avoid first pass metabolism, and easily accessible making it a  successful delivery site for drugs.

Widely used for the delivery of decongestants and anti-histamines.

Fentanyl  is highly lipophilic and is readily absorbed across the mucosal membranes.

Fentanyl pectin  nasal spray provides rapid analgesia for breakthrough pain.

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