Topical agents are the most effective treatments for allergic rhinitis, being maximally effective in one week of use.
Adverse reactions include nasal dryness, burning , sore throat, epistaxis and headache.
The most common adverse effect of a nasal corticosteroids isnasal bleeding less commonly can cause septal erosions and ulcerations.
Have potential to decrease growth velocity in children.
The systemic bioavailability of second generation intranasal steroids is less than 1%.
Intranasal corticosteroids may raise intraocular pressure slightly in some patients who ate at risk for glaucoma or who have glaucoma.
Nasal corticosteroids are, however, not a contraindication in patients with glaucoma.