IL-37, also known as interleukin-37, is a cytokine, which is a type of signaling molecule involved in immune responses.
IL-37 is expressed in most tissues, and non-specifically inhibits the inflammatory response and innate immunity.
It belongs to the IL-1 family of cytokines.
IL-37 is known for its anti-inflammatory properties and its ability to regulate the immune system.
It acts by binding to specific receptors on immune cells, thereby inhibiting the production of pro-inflammatory molecules and promoting the production of anti-inflammatory molecules.
It has been studied for its potential therapeutic applications in various inflammatory and autoimmune conditions, such as rheumatoid arthritis, inflammatory bowel disease, and asthma.
IL-37 shows promise as a potential target for the development of anti-inflammatory therapies.