Ingenol mebutate (Picato)

Picato® (ingenol mebutate) gel, 0.015% or 0.05% is

A clear colorless gel for topical administration, which contains the active substance ingenol mebutate, an inducer of cell death.

Picato® gel, 0.015% and 0.05% contains 150 mcg and 500 mcg of ingenol mebutate, respectively in each gram of gel consisting of isopropyl alcohol, hydroxyethyl cellulose, citric acid monohydrate, sodium citrate, benzyl alcohol and purified water.

Indicated for actinic keratosis

Local skin reactions, including erythema, flaking/scaling, crusting, swelling, vesiculation/pustulation, and erosion/ulceration.

Adverse reactions that occurred in ≥ 2% of subjects.

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