Guaifenesin

Acts as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi.

Stimulates the flow of respiratory tract secretions allowing ciliary movement to carry the loosened secretions upward toward the pharynx.

It may increase the efficiency of the cough reflex and facilitate removal of the secretions.


Brand name Mucinex among others.


A oral medication used to try to help cough out phlegm from the airways.


Acts as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi. 


Use is not recommended in children less than 6 years old.


Elimination half-life 1–5 hours.


Side effects may include dizziness, sleepiness, skin rash, nausea,  vomiting, formation of kidney stones, diarrhea, and constipation.


Works by making airway secretions more liquid.


Nausea and vomiting can be reduced by taking guaifenesin with meals.


The risk of forming kidney stones during can be reduced by maintaining good hydration and increasing the pH of urine. 


Rarely, severe allergic reactions may occur.


Mild dry mouth or chapped lips may also occur when taking  guaifenesin, so drinking a glass of water is recommended with each dose.


It helps the flow of respiratory tract secretions, allowing ciliary movement to carry the loosened secretions upward toward the pharynx.


It may therefore to increase the efficiency of the cough reflex and facilitate removal of the secretions.


It has muscle relaxant and anticonvulsant properties.


It can be taken by mouth as pills or syrups.


 It is also included in many other over-the-counter cough and cold remedy combinations: in conjunction with dextromethorphan, acetaminophen, ephedrine, pseudoephedrine, or phenylephrine.


Combination guaifenesin and pseudoephedrine is sold under the brand name Mucinex D.








Leave a Reply

Your email address will not be published.