Genetic polymorphism

Describes the presence of more than one allele at the same locus.

The least frequent allele is so prevalent that mutations alone cannot account for it.

Base pair variants ref2242ed to as a single nucleotide polymorphism in each individual.

Single nucleotide polymorphisms may identify genotype differences accounting for varied responses to drugs, inflammation or other disease processes.

Pharmacogenomics identifies polymorphisms in drug metabolizing enzymes, drug transporters and receptors influencing how drugs are handled.

Most common form of genetic variation is the single nucleotide polymorphisms (SNPs).

Approximately 10 million common SNPs with a minor allele frequency of at least 5%, are transmitted across generations in blocks, and allow a few SNPs to capture the great majority of SNP variation in each block (Gabriel SB).

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