Primary tumor TX Cannot be assessed T0 No evidence of primary tumor Tis Carcinoma-in-situ T1 Tumor invades the lamina propria or submucosa T2 Tumor invades muscularis propria or subserosa T2a Tumor invades musculris propria T2b Tumor invades the subserosa T3 Tumor penetrates serosa without invasion of adjacent structures T4 Tumor invades adjacent structures Lymph node involvement (N) NX Cannot be assessed N0 No regional lymph nodes metastases N1 Metastases to 1-6 regional lymph nodes N2 Metastases in 7-15 regional lymph nodes N3 Metastases to greater than 15 lymph nodes Distant metastases (M) MX Distant metastases cannot be assessed M0 No distant metastases M1 Distant metastases Staging group Stage 0 Tis, NOM0 Stage IA T1,N0.M0 Stage IB T1,N1,M0 Stage II T1,N2.M0 Stage IIIA T2a/b,N2,M0 Stage IIIB T3,N2,M0 Stage IV T4,N1-3,M0 T1-3,N3,M0 Any T, any N, M1
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