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Gabapentin enacarbil (Horizant)

A pro drug of gabapentin.

An antiepileptic drug.

Associated with increased suicidal thoughts or behavior.

The most common adverse reactions are somnolence/sedation, dizziness, headache, nausea, and fatigue.

A non-dopaminergic treatment for moderate to severe RLS.

600 mg extended release agent is indicated for the treatment of moderate to severe primary RLS in adults.

Not recommended for patients who require sleep during the daytime and to remain awake at night.

Can be discontinued without tapering.

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