The Framingham Heart Study what is the first large scale, multi generational study of cardiovascular risk in the US.
The Framingham Heart Study Has led to the identification of major risk factors for cardiovascular disease, including smoking, high cholesterol, hypertension, physical inactivity, and diabetes.
A specific sex specific risk score that accounts for age, systolic and diastolic blood pressure, total cholesterol level, high density lipoprotein cholesterol level, diabetes diagnosis, and smoking status and coronary heart disease.
A one-unit metabolic equivalent of task (MET) increase in baseline cardiorespiratory fitness resulted in an 18% decrease in cardiovascular mortality in FRS classified low risk adults over 30 year follow up.
Individuals 50 years of age who were without traditional risk factors had a less than 10% lifetime risk of coronary artery disease complications or stroke.