Acute necrotizing parenchymal and or perirenal infection.
Usually caused by Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, and Klebsiella pneumoniae.
Can be caused by Candida, Cryptococcus and Aspergillus fungi associated well.
Typically caused by gas producing bacteria.
More than 90% of cases are associated with diabetes mellitus.
Usually unilateral involvement of the kidney with only 10% of cases bilateral.
Can complicate urinary tract obstruction by stones, neoplasm or stricture.