DNA repair mechanisms

Due to the damaging effects that mutations can have on genes, there are  mechanisms such as DNA (Deoxyribonucleic acid) repair to prevent or correct mutations by reverting the mutated sequence back to its original state.


Mutations can involve the duplication of sections of DNA, usually through genetic recombination.


DNA damages are repaired by the DNA repair system of the cell. 


Each cell has a number of pathways through which enzymes recognize and repair damages in DNA.


The process of DNA repair is an important way in which the body protects itself from disease. 


Once DNA damage has given rise to a mutation, the mutation cannot be repaired.



DNA duplications are a major source of raw material for evolving new genes.



Most genes belong to larger gene families of shared ancestry, detectable by their sequence homology.

DNA repair: The most important or nucleotide excision repair, mismatch repair, basic excision repair, homogous recombination and non-homologous end joining.

Nucleotide excision repair, mismatch repair, and basic excision repair oral eye on him damaged opposite strand DNA to serve as a template for repair of the damaged strand.

Double-strand break repair occurs through homologous recombination and non-homologous recombination- piece mechanisms do not require a template, and can be used in circumstances where no template it exists.

BRCA1 gene plays a role in interstrand crosslink repair through several mechanisms including homologous recombination.

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