Danazol is an antigonadotropin agent with mild androgenic effects.


It is approved for management of breast pain at a dosage of 100-400 mg/d).


It is effective in reducing breast pain symptoms in up to 77% of patients with cyclic breast pain and 31% of patients with noncyclic breast pain.


Side effects include: weight gain, deepening of the voice, menorrhagia, male-pattern hair loss, acne, and muscle cramps.


It has teratogenic effects.


Side effects include: hirsutism, acne and depression.

Utilized for mastalgia, and breast cysts.

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