Cutaneous conditions associated with malignant and benign tumors.

There are many skin conditions that may occur which are associated with cancers, as well as some benign tumors, inside the human body.

Cutaneous conditions associated with internal benign tumors and/or malignancies:

Erythema gyratum repens Lung cancer

Hypertrichosis lanuginosa acquisita Lung cancer

Paraneoplastic pemphigus Non-Hodgkin lymphoma

Chronic lymphocytic leukemia

Castleman’s disease



Tripe palms Lung cancer

Tripe palms with acanthosis nigricans Stomach cancer

Pityriasis rotunda Hepatocellular carcinoma

Migratory thrombophlebitis Pancreatic adenocarcinoma

Acanthosis palmaris Bronchial carcinoma

Sign of Leser–Trélat Gastrointestinal adenocarcinoma

Acquired ichthyosis Hodgkin disease

Pityriasis rotunda Hepatocellular carcinoma

Paraneoplastic pigmentation Small cell bronchial carcinoma

Acrokeratosis paraneoplastica Squamous cell carcinoma of the upper respiratory or gastrointestinal


Necrolytic migratory erythema

Glucagon secreting pancreatic islet cell adenoma

Dermatomyositis Lung cancer in men, breast and gynaecological tumors in women and colorectal cancers in both sexes

Scleroderma‐like skin changes Carcinoid syndrome

Paraneoplastic pemphigus B‐cell proliferations and thymoma or thymoma‐like neoplasms; specifically Non Hodgkin’s lymphoma.

Dermatitis herpetiformis Lymphoma

Porphyria cutanea tarda and variegate porphyrias Hepatocellular Carcinoma

Erythroderma and exfoliative dermatitis Mycosis fungoides or Sézary syndrome

Pyoderma gangrenosum Hematological malignancy

Sweet syndrome

Hematological malignancy

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