Infection of the biliary tract.

Many respond to antibiotics, but many require emergency biliary drainage.

Charcot’s triad of fever, jaundice and right upper quadrant pain.

Reynolds pentad refers to the three above symptoms plus septic shock and mental confusion.

Biliary tract manipulations, interventions, biliary stents are the most common causes, replacing choledocholithiasis.

Can be caused by hepatobiliary malignancies.

Strictures, biliary cysts may be causes.

Mortality rate ranges from 13-88%.

No gender differences.

Median age of presentation 50-60 years of age.

Fever occurs in almost 95% of patients.

Patients may have abdominal pain, jaundice along with fever.

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